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Laczo, J
For instance, lactate induces TGF-2 expression in glioma cells and knockdown of lactate dehydrogenase A (LDHA), an enzyme that catalyzes lactate production, downregulates TGF-2 levels ( TABLE 2 Modulation of TGF- signaling by metabolic changes
10.1002/jps.20625 J
6.2 Computational modeling Computer modeling has emerged as a vital tool for deciphering the dynamics of macrophage polarization and its regulatory strategies, enabling quantitative predictions of complex biological processes by integrating multi-scale data
From these results, it was considered that the gradual increase in ferroptosis leads to the weakening of the overall antioxidant capacity of cells
