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Although the mitochondria-independent pathway driven by GPX4 inhibitors is crucial for understanding and improving cancer treatment, -dependent ferroptosis induced by cysteine deficiency or GSH depletion may be more relevant to the pathophysiological context of chronic human diseases

IB kinase (IKK) is composed of two subunits of IB kinase (IKK and IKK and IKK)

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Treatment depends on the clinical entity and the CTCAE grade (Table 7)

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