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As such, inhibition of lipid biosynthetic pathways has been recognized as a potential therapeutic strategy for impairing tumor growth and viability

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[DOI] [PubMed] [Google Scholar] 75.Brennan CM, Atkins KA, Druzgal CH, Gaskin CM

Upon stimulation by internal or external apoptotic signals, the mitochondrial membrane potential (MMP) is disrupted, resulting in an increase in mitochondrial outer membrane permeabilization (MOMP) and triggering the early events of apoptosis
