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Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance
[Abstract]2025 Mar 29:154:114528
Strategic application methods can improve penetration and results
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It has been determined that when glutamine depletion activates the energy stress AMPK pathway and inhibits mTORC1 activity, this results in the subsequent inhibition of the protein expression level of -TrCP, consequently leading to abnormal cell cycle progression and reduced proliferation [19]
