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Results KAT6A mutations cause a decrease in histone H3 lysine 23 (H3K23) acetylation in human cells and mice To determine the effects of mutation of the KAT6A gene on histone acetylation, we generated human HEK293T cells carrying six different KAT6A variants observed in individuals with ARTHS using CRISPR/Cas9 and homology-directed repair (Tables S1, S2, and S3)
52: 22052212 [DOI] [PubMed] [Google Scholar] 35.Frederich M., Balschi J
Sus propiedades antioxidantes , antiinflamatorias y su potencial para mejorar la recuperacin hacen que sea una opcin interesante para aquellos que buscan optimizar su rendimiento y bienestar general
Elife 7 2018 PMC6056233 Stratiievska A, Nelson S, Senning EN, Lautz JD, Smith SE, Gordon SE
Instead, our findings suggest genetically predicted l-carnitine could be linked to higher risk of CAD overall and in men, and heart failure overall
