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Rutin protects hair cells and spiral ganglion neurons from cisplatin-induced ototoxicity by reducing ROS production after cisplatin exposure, activating PI3K/AKT signalling and inhibiting the JNK/p38/MAPK signalling pathway (Zheng et al., 2022)

Systematic analysis of brain and skull ischemic injury expression profiles reveals associations of the tumor immune microenvironment and cell death with ischemic stroke

[63] Research [edit source] SOD has been used in experimental treatment of chronic inflammation in inflammatory bowel conditions

J Diab Investig

(2010) developed PEGylated PLGA NPs encapsulating PS-341, a FDA approved proteasome inhibitor, which has been firstly employed for cancer therapy, even though recent studies have proved the importance of this class of drugs in pharmaco-gene therapy of CF