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Similarly, both insufficient and supranutritional dosages of selenium supplementation may impair spermatogenesis by regulating PI3K/AKT- mediated apoptosis of testicular cells (135) and weakening the antioxidant capacity of sperm (136)

Veterinary therapy is designed to correct a deficiency and is typically chosen based on lab results and clinical context

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Therefore, the antioxidant defence systems play a vital role in maintaining an optimal redox balance in melanocytes by quenching ROS and protecting against oxidative stress, excessive melanogenesis and photo-damaged skin