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Simultaneously, there is growing interest in refining modulation of the endocannabinoid system beyond plantderived cannabinoids, focusing on developing compounds that selectively target the cannabinoid Type 2 (CB2) receptor to potentially dampen neuroinflammation [422] or those that inhibit fatty acid amide hydrolase to boost levels of the endogenous cannabinoid anandamide [423], aiming for analgesic efficacy with a reduced psychoactive burden

Although the results of the study showed to be promising, they acknowledged limitations in the translation of the in vivo studies to clinical trials due to the difference in the human and mouse physiology

The patients biochemical abnormalities gradually resolved with intravenous fluids, sodium bicarbonate, and discontinuation of acetaminophen

Fujitani K, Ajani JA, Crane CH, Feig BW, Pisters PW, Janjan N, Walsh GL, Swisher SG, Vaporciyan AA, Rice D, Welch A, Baker J, Faust J, Mansfield PF

Yoshii, K., Hosomi, K., Sawane, K