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Dark yellow urine accompanied by symptoms such as dizziness, dry mouth, or passing urine less often than usual suggests dehydration requiring intervention, whereas isolated colour change without other symptoms typically reflects normal concentration variation

Topical application in dry eye offers osmoprotection and modulates immune and inflammatory responses

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References Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, et al

doi: 10.1073/PNAS.0803124105 100 Kalantar-ZadehK.KoppleJ
