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Some of these animal studies suggested minor hormonal changes, but the data is not sufficient to make conclusions about effects in humans

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This is particularly important with colchicine as it is a substrate for CYP3A4 and P-gp and has a narrow therapeutic window

Areas of modest interest have also been linked to areas on chromosomes 1, 6, and X.25 Thus, it is likely that DN, like melanoma, is a complex, heterogeneous trait

Find out how this pigmented skin condition is treated