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doi: 10.1016/j.ttbdis.2019.101270 165

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Although there was no effect on sperm motility or sperm density in the epididymis, there was a significant increase in the percentage of abnormal sperm in mice consuming 1.78 times the MHDD (based on a body surface comparison) and there was a reduction in the number of mating pairs producing a fifth litter at this dose, suggesting the potential for cumulative toxicity with chronic administration of acetaminophen near the upper limit of daily dosing

The spore powder of also exhibited potent cytotoxic effects in the MDA-MB-468, triple-negative breast cancer cell lines, and SUM-102cell line and overexpressing the HER2 gene in MDA-MB435 [73]

Subsequently, slides were stained with DAB solution and counter stained with hematoxylin