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This faulty gene results in slower conjugation of bilirubin in the liver and so it builds up in the bloodstream instead of being excreted through the biliary ducts

PMCID: PMC7140927 Ling V, Snedden WA, Shelp BJ, Assmann SM (1994) Analysis of a soluble calmodulin binding protein from fava bean roots: identification of glutamate decarboxylase as a calmodulin-activated enzyme

Identifying novel targets (synthetically lethal partners, metabolic vulnerabilities, immunotherapies, chemotherapies, signaling pathway inhibitors, upstream or downstream targets) that can be co-targeted with SLC7A11 inhibition in cancer may significantly improve the anti-cancer effects

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Stay informed, engage with the broader scientific community, and be prepared to adapt your protocols as new insights emerge