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The peak also contained a non-synonymous, synonymous, and several intronic SNPs in a damaged DNA-binding protein, MtDDB2 (Medtr5g070310), and an undecaprenyl pyrophosphate synthase MtCPT7 (Medtr5g070270), which is orthologous to AtCPT7 (also known as AtCPT4 )

Clinical and experimental immunology , 170 (2), 194201

2006 Jul;40(7):1250-8

Novel localization of OCTN1, an organic cation/carntine transporter to mammalian mitochondria

A study in adults aged 70 and older showed increased heteroplasmy linked to an increased depression score.[ref] Rare mitochondrial mutations that cause mitochondrial diseases are also linked to major depressive disorder.[ref] In fact, one study of people with hereditary (genetic) mitochondrial diseases showed that 54% had major depressive disorder and 17% had bipolar disorder.[ref] Outside of the mitochondrial genome, genes in the nuclear genome that code for proteins in the mitochondria are also linked to depression