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HEPES Buffered Saline (another common HBS variant) is employed in reconstitution for maintaining isotonicity during experiments involving cell cultures or biophysical assays

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Barbosa MT, et al

Mean SEM of n = 1112 mice

We scoured the medical database looking for reactions to any form of B12, and all we could find were ten cases (which all happened in reaction to either cyano or hydroxy B12, not the other forms)
