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Reflux and bloating also usually feel worse when you lie down

Targeting the gutimmunebrain axis for therapeutics The gutimmunebrain axis has emerged as a crucial target for developing novel therapies for neurological disorders, with increasing evidence underscoring its role in neuroinflammation, immune regulation, and brain function

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In 1870, British gastroenterologist Samuel Fenwick (1821-1902) in London associated stomach atrophy with this form of anemia and demonstrated that stomach mucosa from an affected fresh cadaver could not digest boiled egg white with prolonged incubation, whereas mucosa from a control stomach could do this (139)

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