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acknowledges the National Institute of Health grant R35 GM122506 and the National Institute of Aging grant R21 AG078540
Jiang et al., 2018b)
doi: 10.1186/s41065-022-00235-y 72 DaiHColemanDNHuLMartinez-CortsIWangMParysCet al
Structure of parkin reveals mechanisms for ubiquitin ligase activation
Most endogenous LA is not free but is covalently attached to lysine residues on the enzyme lipoyl domains by forming an amide bond with octanoic acid by the octanoyl transferase in the first step of its biosynthesis [22]
