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Oxidative stress Oxidative stress was first described by Sies (1985) and is defined as an imbalance between the production of reactive oxygen species (ROS) and antioxidant defense

In: GeneReviews((R)), Seattle (WA) Adam M.P., Ardinger H.H., Pagon R.A., Wallace S.E., Bean L.J.H., Gripp K.W., Mirzaa G.M., Amemiya A., editors

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JAMA 310 , 21912194 (2013)

Dasatinib is a classical anticancer drug, a tyrosine kinase inhibitor, which also exhibits senolytic effects [114]
