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Another compound that was identified as potent BACH1-inhibitor was the phytocannabinoid cannabidiol (CBD), which induces nuclear export and degradation of the transcription factor ( In vitro models have confirmed CBDs antioxidant and anti-inflammatory properties, acting through HMOX-1 and inducing the downregulation of pro-inflammatory cytokines (Juknat et al., 2016

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Branch retinal vein occlusion treated by intravitreal triamcinolone acetonide

& Larijani, B

Although we did not identify specific cell populations in our bulk transcriptomic analysis, macrophage activation was predicted in the immunized flight mice when compared to their saline-treated counterparts (Fig