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The thymalin peptide , a related thymic peptide, operates through similar but distinct mechanisms that may also have relevance to immune dysregulation conditions

10.1073/pnas.2637002100 80 XiongC.LiuJ.LinD.ZhangJ.TerrandoN.WuA

Effects on mitochondrial function in tissues like skeletal muscle have been observed within hours, but structural and functional benefits in conditions like AMD, Barth, and kidney disease typically take months of continuous dosing

Smoking is the largest single risk factor: more than 70% of COPD cases occur in current or former smokers, though it is important to note that only 1550% of smokers go on to develop COPD