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Description
Although nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) regularly reduce amyloid pathology and improve cognitive performance in murine models through Sirtuin-mediated mitochondrial biogenesis, their clinical validation is still in its early stages

More recent genome-wide association studies (GWAS) have identified single nucleotide variants (SNV

Commun Med 6 , 315 (2026)

[38] Fasano A

However, a trial in 216 healthy women (25-50 years old) found little benefit of a multivitamin/mineral supplement
