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doi: 10.1007/pl00007853

In the UK, hydroxocobalamin 1 mg intramuscular injection is used: Without neurological involvement : 1 mg three times weekly for two weeks, then maintenance of 1 mg every two to three months With neurological involvement : 1 mg on alternate days until no further improvement in symptoms, then maintenance of 1 mg every two months Lifelong maintenance is required for pernicious anaemia or other irreversible causes of deficiency Oral B12 supplementation may be appropriate for diet-related deficiency in patients without neurological symptoms and with adequate absorption capacity

Note: Wellness injections are not suitable for pregnant or breastfeeding women, those with certain medical conditions, or individuals taking specific medications

doi: 10.1038/jcbfm.1990.47

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