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The disease is called pernicious ( deadly ), because before scientists first isolated B12 (after which, shots became available), it was lethal

J Exp Clin Cancer Res (2009) 28:20

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Special Cases: Athletes, Vegans, and Those with Absorption Issues Athletes Some athletes opt for injections every 2-3 weeks due to higher energy demands

The 2024 NICE guideline asks clinicians to tailor timing to your symptoms and review it, rather than treating one figure as fixed
