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For decades, GPX typically uses glutathione (GSH) as a reducing agent in catalyzing the reduction of H 2 O 2 or organic hydrogen peroxide to water or corresponding alcohols, respectively (Brigelius-Floh and Maiorino, 2013)

Ethics declarations Ethics approval and consent to participate We didnt use any animal or human data or tissue in this article, so ethics approval and consent to participate are not applicable
Some protocols might also use intramuscular injections (into muscle), though subcutaneous is more common due to better tolerability

Of the seven PDX exposed to IACS, five responded with tumour regression or stable disease, whereas two were resistant (Fig
Kluppel MLW, Oliveira MBM.ChagasG
