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Oxidative Stress as an Underlying Contributor in the Development of Chronic Complications in Diabetes Mellitus

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Notably, certain microbial metabolites (e.g., butyrate and acetate) have been shown to reduce proinflammatory cytokines [interleukin (IL)6, IL-12, IL-17, and interferon (IFN)-], while enhancing anti-inflammatory cytokines (transforming growth factor- and IL-10), consequently modulating SLE disease activity [10]

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