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doi: 10.1021/acs.chemrestox.6b00001

Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN- and alpha B-crystallin

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Results GSTM1 shares maximum homology with GSTM2 In our structural homology analysis, the members of the GST superfamily were found to share high sequence homology with each other when examined by ClustalW ( and a domain search using Pfam ( Members of the same class ( i.e ., other GST enzymes) share 7599% sequence identity (maximum homology between GSTM1 and GSTM2 ), whereas the homology is approximately 2530% with different classes ( GST and GST )