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These activated transcription factors assemble into AP-1 complexes that drive transcriptional activation of proinflammatory mediators such as TNF-, IL-1, IL-6 and COX-2 79,80

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Side effects include myelosuppression, hepatotoxicity, fatigue, GI distress, and CNS disturbance (23,24)

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Childrens Hospital of Philidelphia

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The stages of skin cancer range from stage 0 to stage IV

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New datasets continue to be published in open-access repositories such as The International Skin Imaging Collaboration (ISIC), which currently has over 485,000 public images (accessed on 25 Nov 2024) 6

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