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Description
It has been suggested that the enzymes in coffee stimulate bile excretion [13], which if true suggests that a coffee enema may prevent dark bile fluid accumulation in the distal small bowel
When requirement of cobalamin fulfills in body, you observe thickening of coat
added effect of high glucose
With chronic hemolysis, elevated biliary excretion of bilirubin promotes the formation of pigment gallstones (cholelithiasis)
These pathways converge to create a state of chronic OS that further exacerbates insulin resistance and -cell dysfunction, and plasma F2-isoprostanes (markers of lipid peroxidation) correlate strongly with HbA1c levels (Tang et al., 2018)
