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Description
Phase I detoxification uses cytochrome P450 enzymes to break down toxins, but this process often creates highly reactive, intermediate metabolites that are actually more toxic than the original substance
doi: 10.3390/pharmaceutics12030276

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Methionine synthase reductase is encoded by the MTRR (5-methyltetrahydrofolate-homocysteine methyltransferase reductase) gene
Xiong, J
