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However, during the early stages of acute pancreatitis, enterogenic endotoxins and inflammation can propagate to the pancreas and other organs through the gut-pancreas axis, leading to severe consequences (Pasari et al., 2019)

Furthermore, the decreased extracellular levels of MT3 observed in AD may facilitate hypermetallation of amyloid- by zinc
Kong X, Thimmulappa R, Craciun F, Harvey C, Singh A, Kombairaju P, Reddy SP, Remick D, Biswal S (2011) Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis

Cattaneo C, Jost WH
doi: 10.1371/journal.pone.0183509 36