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Additional research is also needed to assess the long-term safety profile of melatonin in children and adolescents [3,137]
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The optimal separation conditions were found using a mobile phase composed of acetonitrile, methanol, and water (43:10:47, v/v/v)
Meta-analytic reviews also highlight substantial variability across studies, reflecting methodological differences and population heterogeneity 99
Ikoma Y, Kusumoto-Yoshida I, Yamanaka A, Ootsuka Y, Kuwaki T
