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The number of adrenergic receptors expressed in IL-1Ra gene knockout (IL-1RA KO) mice showed complex stage changes (89)
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The next day, 10% FBS containing RPMI 1640 medium was added, and cells were treated with 10 ng/ml TNF-, with and without NR 250 M, and incubated for 24 h
When applied in the condition of the already established severe acute pancreatitis, an obvious salutary effect was consistently noted
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