l carnitine cause weight gain L-Carnitine Supplements: Benefits, Dosage and Food Sources L-CARNITINE increases muscle mass, reduces

Data availability The data generated in this study are available within the article and its Supplementary Data files

PubMed CrossRef Herrera D, Mayet L, Galindo MC, et al

Nrf2 is a novel regulator of bone acquisition

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Table 2 Treatment Emergent Symptom Incidence InpatientsOutpatients T1 P2 T3 P4 Number of Patients 142 95 157 158 % of Patients Reporting Allergic Skin Condition/Edema 2.8 1.1 7.0 1.3 Autonomic Blurred Vision 6.3 4.2 14.7 3.8 Constipation 7.0 4.2 7.6 5.7 Dry Mouth 14.8 8.4 33.8 20.3 Cardiovascular Hypertension 2.1 1.1 1.3 *5 Hypotension 7.0 1.1 3.8 0.0 Shortness of Breath *6 1.1 1.3 0.0 Syncope 2.8 2.1 4.5 1.3 Tachycardia/Palpitations 0.0 0.0 7.0 7.0 CNS Anger/Hostility 3.5 6.3 1.3 2.5 Confusion 4.9 0.0 5.7 7.6 Decreased Concentration 2.8 2.1 1.3 0.0 Disorientation 2.1 0.0 *7 0.0 Dizziness/Lightheadedness 19.7 5.3 28.0 15.2 Drowsiness 23.9 6.3 40.8 19.6 Excitement 1.4 1.1 5.1 5.7 Fatigue 11.3 4.2 5.7 2.5 Headache 9.9 5.3 19.8 15.8 Insomnia 9.9 10.5 6.4 12.0 Impaired Memory 1.4 0.0 *8 *9 Nervousness 14.8 10.5 6.4 8.2 Gastrointestinal Abdominal/Gastric Disorder Bad Taste in Mouth 1.4 0.0 0.0 0.0 Diarrhea 0.0 1.1 4.5 1.9 Nausea/Vomiting 9.9 1.1 12.7 9.5 Musculoskeletal Musculoskeletal Aches/Pains 5.6 3.2 5.1 2.5 Neurological Incoordination 4.9 0.0 1.9 0.0 Paresthesia 1.4 0.0 0.0 *10 Tremors 2.8 1.1 5.1 3.8 Sexual Function Decreased Libido *11 1.1 1.3 *12 Other Decreased Appetite 3.5 5.3 0.0 *13 Eyes Red/Tired/Itching 2.8 0.0 0.0 0.0 Head Full-Heavy 2.8 0.0 0.0 0.0 Malaise 2.8 0.0 0.0 0.0 Nasal/Sinus Congestion 2.8 0.0 5.7 3.2 Nightmares/Vivid Dreams *14 1.1 5.1 5.7 Sweating/Clamminess 1.4 1.1 *15 *16 Tinnitus 1.4 0.0 0.0 *17 Weight Gain 1.4 0.0 4.5 1.9 Weight Loss *18 3.2 5.7 2.5 1 T=Trazodone HCl 2 P=Placebo 3 4 5 Incidence less than 1% 6 7 8 9 10 11 12 13 14 15 16 17 18 Occasional sinus bradycardia has occurred in long-term studies