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Mangiferin attenuates osteoporosis by inhibiting osteoblastic ferroptosis through Keap1/Nrf2/SLC7A11/GPX4 pathway

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Nature 576 (7787), 482486

Finally, in this study, the focus was on circulating immune cells, in monocytes/cDC in particular, our area of expertise, but we do not exclude that energy metabolism imbalance could be relevant in other immune cells such as macrophages and plasmacytoid DC 64 and/or have disruptive effects in non-circulating cell types, such as neurons or glial cells during brain development in AGS patients