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Description
Excretion: Esomeprazole has a plasma elimination half-life of about 1-1.5 hours

Homocysteine can then be recycled back to methionine by the enzyme methionine synthase (also known as 5-methyltetrahydrofolate-homocysteine methyltransferase) in a reaction that requires folate in the form of 5-methyltetrahydrofolate as the methyl donor and vitamin B12 in the form of methylcobalamin as a cofactor

J Am Acad Orthop Surg

B-12 is prepared and packaged to support consistent handling in controlled research environments
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