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Sever et al

The thousands of anecdotal human reports suggest similar effects to animal studies, but formal human clinical trials remain lacking

Mutant p53 is found to be linked in regulation of angiogenic response during the tumor progression via ROS mediated activation of VEGF-A and HIF-1 in human colorectal carcinoma cell line HCT116 [59]

Maggini S, Pierre A, Calder PC

Numerous studies have proposed that GHK-Cu acts as a potential SIRT1 activator, thereby highlighting its multifaceted role in cellular processes, especially its capacity to enhance SIRT1 activity ( in vivo and in vitro experiments
