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10.1523/jneurosci.23-08-03394.2003 J

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These conditions are also typified by loss of mitochondrial health through dysfunction of homeostatic components such as mitophagy, unfolded protein response, and the antioxidant system

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The company has two lead programs in its pipeline: 2B3-101 (now 2X-111 at Oncology Venture A/S) for recurrent malignant glioma has completed a Phase I/IIa clinical trial for brain metastases, and 2B3-201 (now ENX-201 at EnhanX Biopharm Inc.), which has completed a Phase I clinical trial in healthy volunteers for acute relapses of multiple sclerosis

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