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Those who experienced severe GI side effects on tirzepatide or semaglutide that required treatment discontinuation should proceed with extreme caution, as the combination will likely produce similar or potentially more pronounced effects
The copper component is biologically essential and tightly regulated research data suggests GHK-Cu actually helps regulate copper metabolism rather than causing copper accumulation

The trials indicated that all doses of tirzepatide resulted in greater weight loss and enhanced glycemic control in comparison to placebo
