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When used with pemetrexed, B12/folic acid therapy further increases sub-G1 populations in human adenocarcinoma and large-cell carcinoma cell lines, independent of p53 status (28)

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10.1099/0022-1317-79-4-731 298 WangQ.QinX.FangJ.SunX

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Data from clinical observations and preclinical animal models suggest a step-wise process leading to autoimmune RA 17

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