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According to the American Cancer Society (ACS), it can have a Chemotherapy injections may cause typical injection site reaction symptoms, including: skin discoloration swelling itching tenderness warmth However, chemotherapy drugs sometimes cause a symptom known as extravasation, which is when the medication leaks from the vein and into the surrounding tissue

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The absorption process is significantly hindered in conditions such as pernicious anemia, Crohns disease, celiac disease, and following ileal surgical resection, all of which can impair B12 absorption and contribute to suboptimal supplementation outcomes