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At low doses, it works by briefly blocking opioid receptors, which may lead to a rebound increase in the bodys production of endorphins and enkephalins

Useful soft tissue endpoints include: muscle fibre organisation vascular response inflammatory marker panels collagen deposition fibroblast activity oxidative stress markers histology scoring cell migration These research areas overlap with tendon and ligament studies but focus more broadly on tissue integrity and repair-associated signalling

Some individuals experience injection site reactions or sensitivity to components of the injection