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Acknowledgements The authors of this work were supported financially by the Research Grants Council of Hong Hong and Tam Sai Kit Endowment Fund (Y.-C.H and K.D.K.L) and by the European Community (FP7,2007-2013) under grant agreement no

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Introduction Synaptic vesicle (SV) recycling, one of the most complex and well-regulated processes at neuronal presynapses, is responsible for the efficient and rapid release of neurotransmitters by exocytosis and the subsequent reuse of SVs 1
