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Keep dry and at room temperature (59-86F [15-30])

Moreover, inhibiting fumarate hydratase, a critical enzyme of the citric acid cycle (CAC), reduces the long-term repopulating potential of HSCs (15)

Differential guide scores in the indicated cell lines upon treatment with 20 M BSO (right)

A prior study identified six putative phosphorylation sites (S155, T189, T216, S246, S284, T292) within ArfGAP1 by mass spectrometry yet no quantitative analysis was provided, and it was unclear which LRRK2 variants were used in these assays, including whether comparison to a kinase-inactive LRRK2 negative control was included (Xiong et al., 2012)

This trait should be preferable for purification of the ERG produced, which is necessary for practical ERG manufacturing in an industrial process, which is the goal of this study