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Network Biology and Polypharmacology of LC LC targets the expression of several genes throughout its production and biodegradations, and it also regulates the expression of several genes such as ACADM, ACADS, CPT1A, CPT1B, CPT1C, SLC25A20, CRAT, and BBOX1, and thus medium-chain acyl-CoA dehydrogenase is an enzyme made possible by the ACADM gene (MCAD)

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Patients with these mutations may benefit from more personalized treatment strategies and close clinical monitoring to ensure optimal thyroid hormone replacement