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during chromosome replication, DNA-replicating enzymes cannot continue replication to the very end of the chromosome, so with each replication the chromosome end is shortened (this is because the synthesis of fragments requires the attachment of RNA primers to the lagging strand)

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Problem 2: Wasting money on weak or no results Fix: Third-party testing helps verify identity and purity, but purity alone does not determine biological effects

doi: 10.1136/jnnp.2009.198192
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