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Interestingly, a three-hour exposure to PFAS in-vitro did not affect the sperm functional profile, in terms of capacitation or fertilization rates, but did significantly delay the developmental progression of in-vitro fertilized day 4 preimplantation embryos, which suggested an alternative stress-mediated impact at fertilization

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Recent developments in our understanding of these pathways provide novel translational opportunities for drug development, dietary intervention, and biomarker identification of human cancers

For DR, Cheng et al