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6) using PROPKA, C23 was determined to be the most acidic cysteine ( p K a = 5.4) followed by C8 ( p K a = 7.4), both of which are more acidic than the thiol group in GSH ( p K a = 8.7)
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[DOI] [PubMed] [Google Scholar] Sithigorngul P, Burton P, Nishihata T, Caldwell L
