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It concurrently raises pivotal antioxidants by activating the Nrf2 pathway, thus scavenging excessive cellular free radicals

CALCIUM + COLLAGEN VOLUME COMPLEX: Formulated with Calcium, Adenosine, Collagen Extract, and Elastin to help restore visible firmness and volume where skin has lost elasticity over time CLINICALLY TESTED ON 5 TYPES OF EYE WRINKLES: In a consumer clinical study, one application of the Cemenrete Calcium Duo showed visible improvement in wrinkle count, area, length, width, and depth around the eye area MULTI-USE SMOOTH CORE STICK: One easy-glide balm stick for the eye area, nasolabial folds, forehead, and neck replenish firmness anytime, anywhere without fingers or mess TARGETS UNDER-EYE HOLLOWS & SAGGING: Adenosine helps support collagen and elastin production to visibly fill sagging areas, while Collagen Extract helps maintain skin thickness and density KOREAN DERMA-COSMETIC FORMULA, PAIRS WITH EYE PATCH: A lightweight, non-greasy 9g stick from DR.MELAXIN's Calcium line layer with the Calcium Volume Eye Patch (Step 1 Balm, Step 2 Patch) for a complete eye routine

CD40 is predominantly expressed in the pro-inflammatory M1 phenotype of macrophages (169), and plasma CD40 levels are correlated with carotid artery severity