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Hauptman M, Gaffin JM, Petty CR, Sheehan WJ, Lai PS, Coull B, Gold DR, Phipatanakul W

Collectively, these data suggested the limited activity of CB-839 monotherapy in CLL cell lines

A total of 98 G6PD-associated genes were identified, and out of the 47 implicated signaling pathways, seven were highly likely to be regulated by G6PD-associated genes

The model was conditioned with a medium corresponding to the concentration of metabolites present in human blood (Supplementary Data 11) 60

However, because of the narrow therapeutic window for acute liver injury and the side effects of NAC, its clinical application has great limitations (Du et al., 2016)
