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Description
ICs are essential for maintaining self-tolerance by controlling immune reaction type, magnitude, and duration ( + fibrocytes, which have a crucial role in the progression of TED, also constitutively express MHC II, B7, PD-L1 ( 2 Overview of thyroid eye disease TED has been plaguing scientists and physicians around the world for nearly two centuries since its discovery ( 3 Implication of immune cells in pathogenic mechanism of thyroid eye disease In the initial stages of TED, a combination of genetic and environmental factors contribute to the development of intolerance to TSHR ( OFs are the main culprit of pathological changes in TED orbital tissue
ZC: Investigation, Writing review & editing
We proceeded to fill this gap by using the newly developed high-resolution sequencing method 36,37
Our spectral model is described in more detail elsewhere
Treatment For people who have iron deficiency, iron supplements are advised (Marshall et al., 2019)
