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For example, the encapsulation procedure may damage the inner membrane or surface structure of RBCs, or the biocompatibility may decrease, leading to phagocytosis along the delivery route

[1] [2] It is administered once weekly via subcutaneous injection and should be used alongside diet, physical activity and behavioural support

4.1 Limitations and implications for practice This meta-analysis has several limitations that should be considered when interpreting the findings

Experts recommend starting with low doses between 0.3mg and 2mg, taken 30 minutes to one hour before bedtime